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Psychic derangements may appear when corticosteroids are usedranging from euphoriainsomniamood swingspersonality changesand severe depressionto frank psychotic manifestationsAlsoexisting emotional instability or psychotic tendencies may be aggravated by corticosteroids.

The following adverse reactions have been reported with dexamethasone or other corticosteroids:

Patients who are on corticosteroids are more susceptible to infections than healthy individualsThere may be decreased resistance and inability to localize infection when corticosteroids are usedInfection with any pathogenviralbacterialfungalprotozoan or helminthicin any location of the body may be associated with the use of cort

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