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CommentsThe XL sustained-release formulation should be administered once daily at bedtimeapproximately 10 PMand should be taken consistently either on an empty stomach or with foodDose titration should be done gradually until adequate blood pressure control is achievedThe recommended dosing is the same whether used alone or added to a diureticThe time needed for full hypertensive response to a given dosage is variable and may range from a few days to several weeksWhile twice daily dosing of the immediate release formulation is effective and can maintain a reduction in blood pressure throughout the daysome patientsespecially when lower doses are usedmay experience a modest rise in blood pressure toward the end of the 12 hour dosing intervalThis can be evaluated by measuring blood pressure near the end of the dosing interval to determine whether satisfactory control is being maintained throughout the dayIf control is not adequatea larger doseor 3 times daily therapy may achieve better control.
Difficulty breathing or swallowing rash blistering or peeling skin hives itching swelling of the facethroattongueor lips feeling faint weight gain irregular heartbeat.
UsesFor the treatment of proliferating infantile hemangioma requiring systemic therapy.
DisclaimerOur goal is to provide you with the most relevant and current informationHoweverbecause drugs affect each person differentlywe can not guarantee that this information includes all possible side effectsThis information is not a substitute for medical adviceAlways discuss possible side effects with a healthcare provider who knows your medical history.
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propranolol is a noncardioselective beta-adrenergic antagonist that has been recently reported to prolong the qtc interval on the surface electrocardiogram in humans when overdosed farhangi, v.